The key/heyhole analogy — I guess what happened with me is I’d learned about the issue with protein folding and had my computer set up to participate in Folding @ Home before I’d heard about the key/keyhole analogy and was working at the pharmaceutical company where they were reversing the chirality of patented drugs about to expire in order to get another 7 years of prescription sized cash… and sometimes reversing the chirality had weird side effects but it usually worked…
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so i always saw it as a combination lock i guess
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