No, it’s a self-reprimand
… [read full article]Posts tagged with '115 Time'
I have an active inner voice. Never stops yapping but I like it. For two weeks of my life, I was on Wellbutrin. [ended up having a full body bad reaction to it after 2 weeks – it was a generic so it probably had oddities in it). While on Wellbutrin, there was absolute inner silence. I don’t remember much of that period of time because there is images but no dialog in my memory. The world was more interesting than my thoughts, which I remember couldn’t fully form; I’d get a half a sentence and it would be gone.
I have an active
… [read full article]There’s just no echo to your auditory system. You read and understand it without also having a confirmation echo. It’s like losing your scribe. That’s what that period of time was like; my inner scribe was dead for two weeks
There’s just no echo … [read full article]
concretizing mindset: IPS, left precentral gyrus, pre-SMA magnitude processing (space/time): bilateral insula, the pre-SMA, the right frontal operculum and the IPS HOW (vs why) OH! HELLO MAGNITUDE. Walsh: 2003: “A theory of magnitude: common cortical metrics of time, space and quantity” and |”According to the ATOM, formulated by Walsh more than fifteen years ago, there is a common system of magnitude in the brain that comprises regions – such as parietal cortex – shared by space, time and other magnitudes (Beudel, Renken, Leenders, & de Jong, 2009; Bueti & Walsh, 2009; Walsh, 2003). The present meta-analysis clearly identified the presence of a set of brain regions that are commonly recruited in both space and time. This system includes bilateral insula, the pre-SMA, the right frontal operculum and the intraparietal sulci. Our study supports and updates the ATOM theory, as it showed not only overlapping activations between space and time but also revealed that spatial and temporal processing is arranged and organized along well-defined spatial gradients in the brain (see Figure 5). For this reason, we now refer to Walsh’s theory as ‘GradiATOM’ (Gradient Theory of Magnitude). ‘GradiATOM’: Functional gradients underlying space and time We found that pre-SMA, right inferior frontal gyrus (IFG), left precentral gyrus and intraparietal sulci represent the areas of activation overlap with spatial gradients, along which space and time are mapped and organized in the brain. More specifically, the SMA showed an anteriorposterior gradient, with space activating more anterior regions (i.e., pre-SMA) and time activating more posterior regions (thus, SMA-proper to greater extent). Frontal and parietal regions showed a dorsal-ventral gradient. Space processing is supported by dorsal frontal and parietal regions, whereas time is more likely to recruit ventral frontal and parietal regions. and from a neural correlates of concrete vs abstract “Neural activity associated with concretization {(How > Why) \ (Exemplars > Categories)} In order to find the neural correlates associated with a concretizing mindset, we searched for the conjunction of neural activity associated with the How > Why and the Exemplars > Categories contrasts. The results showed that a concretizing mindset recruits parts of the fronto-parietal action network: the IPL, the left precentral gyrus and the pre-SMA (Figure 1 and Table 2).” concretizing mindset: IPS, left precentral gyrus, pre-SMA magnitude processing (space/time): bilateral insula, the pre-SMA, the right frontal operculum and the IPS also: “the midinsula and the frontal operculum make up the taste cortex (TC), which encodes the features of pure taste stimuli such as quality and intensity “
concretizing mindset: IPS, left
… [read full article]So to focus, one has to ignore – a lot. The more inputs you have coming into you simultaneously from different directions with insufficient (normal) barriers to entry, the possibilities become overwhelming. Of course, big picture, life is short, so that’s certain. Slightly smaller picture, if time is scarce and you have to eat to survive but you want to thrive and not just survive, time becomes a commodity to spend towards increasing whatever the metrics for thriving might be at the cost of the time used for the effort. So, it goes to a question of purpose.
So to focus, one
… [read full article]born at 28W. A week earlier, bioelectric activity had burst discharges. OH! myelination! Basically, uninsulated wires to insulated wires? but then there’s the gap – “For example, a characteristic pattern of a very early stage of bioelectrical development (24–27 W) is the discontinuous bioelectrical activity with burst discharges (Dreyfus-Brisac, 1968). The EEG of a 27-week-old premature infant is mainly discontinuous; interburst intervals tend to decrease with increasing conceptional age, and the bursts are synchronous between hemispheres in 80–100% of recording epochs (Anderson et al., 1985). The main features of EEG maturation in preterm infants (29–38 W) are a progressive spatio-temporal differentiation, a decrease in discontinuous activity with burst discharges, and an increase in various rhythmic activities (Nolte and Haas, 1978; Cioni et al., 1992; reviewed in Kostovic´ et al., 1995). The developmental peak of the SP (28–30 W) sees the onset of intense dendritic differentiation of layer III cortical neurons, concomitant with the penetration of various classes of afferent fibers in the CP. This suggests that ingrowing afferents may be involved in the induction of the dendritic differentiation of cortical neurons between 27 and 32 W. The ingrowth of commissural and associative corticocortical fibers may also explain the rapid increase in length and arborization of the basal dendrites of layer III cortical neurons during this period, as these neurons are both the main source and the target of corticocortical connectivity (Mrzljak et al., 1990, 1992) “
born at 28W. A
… [read full article]7.9% in a 24-week-old fetus. This drops to 2.53% in a 28-week-old fetus, being the only numerical value that differs in 24- and 28-week-old fetuses (Table 2). There are two distinct populations of labeled cells in the IGL, one with smaller cell nuclei and one with larger cell nuclei (Fig. 2C and D). Labeled cells with large cell nuclei locate mainly below the Purkinje cells (Fig. 2C and D) but a few are found at the border between the IGL and WM. At this age the border between those two layers is hard to distinguish, therefore, it is difficult to measure the exact width of the IGL. Large numbers of small Ki-67 immunopositive cells occurred inside the WM. In addition to cell proliferation in the secondary germinal layer (EGL) and in the other cerebellar cortical layers, an intensive cell proliferation occurs in the primary germinal layer of the ventricular zone (Fig. 2B). The lamina dissecans disappears between the 28th and 32nd weeks, as was observed by Rakic and Sidman [20]. As a consequence, the cerebellar cortex of a 32- week-old fetus consists of four layers Fig. 2. Photomicrographs of Ki-67 labeled neurons in the cerebellum of 24- (B, C) and 28-week-old (A, D) fetuses. (A) In the cerebellum of the 28-week-old fetus most of the cells in the EGL (e) are immunoreactive for Ki-67. In the IGL (i) the labeled cells locate close to the layer of Purkinje cells (p). Only a few labeled cells (arrows) are in the deep part of the IGL. The square indicates the magnified area shown in D. (B) Ventricular (vz) and subventricular zones of the fourth ventricle still contain large number of immunoreactive cells at this age. (C) In the EGL (e) of the cerebellum of a 24-week-old fetus, the outer and inner zones are clearly separated (dotted line). The IGL (i) contains two populations of labeled cells, one with large, ovoid cell nuclei (arrows) and another with small, round cell nuclei (open arrows). Curved arrows mark the most lightly stained cells that are accepted as specifically labeled in this study. (D) Higher magnification of the area indicated by the square in A. Labeled cells mainly locate in the outer zone of the EGL (above the dotted line). The IGL (i), below the lamina dissecans (ld), contains a heterogonous population of Ki-67 labeled cells displaying large (arrow) or small cell nuclei (open arrows). Scale bars=90 mm for A; 50 mm for B; 30 mm for C and D. Abbreviations used in the figure are e, external granular layer; i, internal granular layer; ld, lamina dissecans; m, molecular layer; p, Purkinje cell layer; vz, ventricular zone.
7.9% in a 24-week-old … [read full article]