PCC Activation is Related to Being Caught Up in Mental Content
PCC Activity is Associated with Self-Related Processing
What is it like if someone asks if you think you’re “outgoing,” “patient,” or “nosy”? Are we attached to certain concepts of ourselves? Do we get caught up in these evaluations? What is this experience like and how does this map onto our brain activity?
“Regions of interest overlayed on term-equivalent T2-weighted images located in the (a) optic radiations, (b) anterior and posterior limbs of the internal capsules, (c) frontal lobes (forceps minor), (d) corpus callosum, (e) cingulum bundles, (f) centrum semiovale, (g) superior temporal lobes (anterior) and inferior temporal lobes (posterior) and (h) orbitofrontal region.”
“Similarly, impairment in two developmental measures at 2 y of age was associated with higher FA in two WM regions. Impaired social–emotional competence on the ITSEA was associated with higher FA in the left cingulum, primarily related to lower radial diffusivity. This domain assesses several core symptoms of autism spectrum disorder (ASD), including empathy, imitative play, prosocial behavior, and attention. ITSEA subscales are markedly abnormal in children with ASD (23), and the cingulum bundles are one of the most abnormal WM regions in those with autism (24). They are one of the major WM tracts connecting intrahemispheric association regions like the cingulate cortex with limbic structures in the temporal lobe (24), and abnormalities of the temporal lobe have been associated with both the social impairment (25) and executive function deficits of those with ASD (26). Prior work investigating other WM regions demonstrated higher FA associated with ASD symptoms. Higher FA was reported in the WM of 6-mo-old infants who later developed ASD (27) and specifically in the cingulum of young children with ASD (28). Our finding was specific to the left cingulum bundle, which is consistent with prior work reporting higher FA predominantly in regions in the left hemisphere among toddlers with ASD”
“higher FA in the right inferior temporal lobe was related to impairment in motor scores, particularly fine motor scores. “
“Regional white matter development in very preterm infants: perinatal predictors and early developmental outcomes”