Oh, I think most of the major ones continue, transforming but continuing. Roman Empire’s changed hands a bunch of times but it’s all traceable.
Some civilizations get resurrected as the mythology carries it forward.
But you want destroyed? REALLY destroyed?
1565: “The city was pillaged, looted and burnt for six months after the war, then abandoned as ruins, which are now called the Group of Monuments at Hampi.”
It was never reoccupied.
Literal, actual Scorched Earth.
Total population loss as far as I know. I learned about it on a video of “world cities”. This single battle knocked this whole city off the map.
Nah Fall of the city was the total loss of the empire, https://en.wikipedia.org/wiki/Vijayanagara_Empire