I worked for big pharma for a few years. I know how they think – that’s why I’m giving them extra skepticism. I almost transferred to Genetech – I’m afraid to see what they’re doing now.
You know what they’re like. Busy busy places. Loads of fun to work for – and everybody’s overpaid, which was great. I didn’t complain, although that might’ve changed, I dunno.
The workers are on the money. It’s the upper decision-making that gets wonky. But they want to avoid lawsuits – their only enemy (not regulations) – so they stay in compliance.
Development of Claritin/Clarinex, which was my era, was interesting. The whole thing is designed to be as WEAK as possible without being placebo. Quite genius really. By being super weak, you don’t get the drowsiness you get from normal antihistamines yet for most problems, it works “good enough”.
Less effective drug but it gets out of your way and lets you live with only a dry mouth? Smart. Weak and smart.
Their competitor for Viagra on the other hand, didn’t work so well. It was JUST shy of beating placebo, which is hard to beat but it couldn’t quite get it up high enough.