coffee for copper and magnesium I stumbled upon years ago while researching and a combination of b12 magnesium and zinc works well for me – just regular amounts.
It works as an anti-anxiety pill might. I’d take it before going to the dentist for example.
I’m fairly certain nicotine helped but I put smoking aside maybe two years ago (stale packs sit in a drawer just waiting) after 25 years in a row.
Being born premature (around 6.5 months) likely caused blooming of local neuronal connections but with poor cross connectivity.
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Human Hippocampal CA1 Involvement during Allocentric
Encoding of Spatial Information
https://www.jneurosci.org/content/jneuro/29/34/10512.full.pdf
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Last, our findings are consistent with computational models proposing that CA1 integrates previously learned information (encoded in CA3) with incoming novel information from the neocortex (via ERC) (Levy, 1989; Vinogradova, 2001). Navigating through a novel spatial environment requires integrating multiple spatial relationships into a flexible memory representation. Forming an allocentric cognitive map requires integration of previously learned viewpoints with newly encountered viewpoints to update the memory representation into one that is independent of starting point. This process would thus presumably recruit more cells within CA1, leading to a detectable fMRI response. I
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“Last, our findings are consistent with computational models proposing that CA1 integrates previously learned information (encoded in CA3) with incoming novel information from the neocortex (via ERC) (Levy, 1989; Vinogradova, 2001).
Navigating through a novel spatial environment requires integrating multiple spatial relationships into a flexible memory representation. Forming an allocentric cognitive map requires integration of previously learned viewpoints with newly encountered viewpoints to update the memory representation into one that is independent of starting point. This process would thus presumably recruit more cells within CA1, leading to a detectable fMRI response. “
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ME:
Ah ha! If I have malfunctioning CA1 from being premature and exposed to less oxygen (or more) at critical periods, it would be difficult to form allocentric map: that is, taking in multiple perspectives (From invisible people) all at once and forming a collective “god’s eye” viewpoint: inference.
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Building concepts one episode at a time: The hippocampus and concept formation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803467/
Notably, the work reviewed here implicates anterior hippocampus in concept formation. Not only has this region been shown to form integrated neural codes that capture commonalities across individual experiences [14, 31, 32], it has also been associated with uncertainty during concept learning [11]. Relatedly, more complex memory functions that rely on integrating and organizing prior experiences such as autobiographical memory [51], schematic representation [52], and imagining the future [53, 54] have been distinctly associated with anterior hippocampus. Anatomically, anterior hippocampus is well suited for the operations that mediate concept formation. Place fields in anterior hippocampus have broad receptive fields [55], potentially allowing for representations that generalize across episodes and behavioral relevance [56]. Anterior hippocampus also has anatomical connections to anterior temporal and medial prefrontal cortices [57], areas that may be involved in the retrieval of previously-learned conceptual/schematic information during new learning [56]. Although future studies are needed to fully characterize the functional properties of anterior hippocampus, and how they differ from posterior hippocampus, the current evidence suggests it may play an important role in concept formation.
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