BAYESIAN MAJOR DEPRESSION?!: Stunned by a Bayesian description of ocd/anxiety/worry that makes sense to me, I found one for major depression (which I don’t have but those that do can see if this rings true for them). Never liked Bayesian but I’m starting to ‘get it’. “We present evidence suggesting that this learning mechanism is distorted in depression: current research indicates that people with depression tend to negatively reappraise or disregard positive information that disconfirms negative expectations, thus resulting in sustained negative predictions and biased learning. We also review the neurophysiological correlates of such deficits in processing prediction errors in people with depression. Synthesizing these findings, we propose a novel mechanistic model of depression suggesting that people with depression have the tendency to predominantly expect negative events or experiences, which they subjectively feel confirmed due to reappraisal of disconfirming evidence, thus creating a self-reinforcing negative feedback loop. Computationally, we consider too much precision afforded to negative prior beliefs as the main candidate of pathology,”

BAYESIAN MAJOR DEPRESSION?!: Stunned by a Bayesian description of ocd/anxiety/worry that makes sense to me, I found one for major depression (which I don’t have but those that do can see if this rings true for them). Never liked Bayesian but I’m starting to ‘get it’.
 
“We present evidence suggesting that this learning mechanism is distorted in depression: current research indicates that people with depression tend to negatively reappraise or disregard positive information that disconfirms negative expectations, thus resulting in sustained negative predictions and biased learning. We also review the neurophysiological correlates of such deficits in processing prediction errors in people with depression. Synthesizing these findings, we propose a novel mechanistic model of depression suggesting that people with depression have the tendency to predominantly expect negative events or experiences, which they subjectively feel confirmed due to reappraisal of disconfirming evidence, thus creating a self-reinforcing negative feedback loop. Computationally, we consider too much precision afforded to negative prior beliefs as the main candidate of pathology,”

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